What does Psalm 5:6 mean?

God destroys liars and abhors the man who spills an innocent person's blood. He also abhors the deceitful person.

In the time of Noah, the human race pursued evil and entertained evil thoughts. God was so outraged by the evil that He destroyed all human life, except the lives of Noah and his family. Genesis 6:5 says, "The LORD saw that the wickedness of man was great in the earth, and that every intention of the thoughts of his heart was only evil continually…So the LORD said, 'I will blot out man whom I have created from the face of the land'" (Genesis 6:5, 7). In His anger, the Lord sent a massive flood to sweep away all life from the earth.

David was confident that the Lord would destroy his deceitful and bloodthirsty enemies. Only those who accept Christ can be identified by His goodness, rather than by their own sin (John 3:16–18; 1 Corinthians 6:9–11). Someday, every unrepentant deceitful, bloodthirsty person will face a sentence of eternal punishment (Revelation 20:10–15).