What does Psalm 38:4 mean?

Sinless perfection is not something we can attain in this life. A true believer may still sin, but when they do so, that experience will come with conviction and God's correction. In that spirit, David laments his sinning (Psalm 38:18). He feels the shame and guilt of his sin such that it seems overwhelming.

When a believer sins, the Holy Spirit convicts, and the sinner should feel a certain burden as a result. As David did, the repentant believer can long to have the Lord lift that weight. Fortunately, Jesus lifts the crushing pressure of shame and guilt and gives peace to anyone who comes to Him in faith. In Matthew 11:28 Jesus says: "Come to me, all who labor and are heavy laden, and I will give you rest." Writing prophetically about Jesus' crucifixion for our sin, Isaiah portrays iniquity being laid on the Messiah, Jesus. He writes "All we like sheep have gone astray; we have turned—every one—to his own way; and the LORD has laid on him the iniquity of us all" (Isaiah 53:6).