What does Psalm 22:10 mean?

The most vulnerable time of a person's life is when they are newborn. Here, David describes his personal relationship with God from birth, that weakest time of life (Psalm 22:9). It's important to note that David has continued to trust God in adulthood, though it seemed that God had abandoned him (Psalm 22:1–2). This statement is part of David's response to the sneers of his enemies (Psalm 22:6–8).

Jesus the Messiah had a lifelong relationship with God, His Father. When Gabriel foretold Jesus' birth to Mary, he said, "The Holy Spirit will come upon you, and the power of the Most High will overshadow you; therefore the child to be born will be called holy—the Son of God" (Luke 1:35). When Jesus was just an infant, King Herod gave orders to kill all the male children from birth to two years old, but God rescued the infant Jesus by directing Joseph in a dream to take Jesus and Mary to Egypt (Matthew 2:13). The family stayed in Egypt until God informed them that Herod had died and it was now safe to return to Israel (Matthew 2:19–20). God never ceased to be Jesus' Father God, even when Jesus was made sin for us (2 Corinthians 5:21; Matthew 27:46; Psalm 22:1).