What does Psalm 139:10 mean?

The prior verse affirmed God would be present, even in the far reaches of the Mediterranean Sea, to guide and protect (Psalm 139:9). Isaiah 58:11 promises God's people, "The LORD will guide you continually and satisfy your desire in scorched places and make your bones strong; and you shall be like a watered garden, like a spring of water, whose waters do not fail."

God is with believers today, as well. He offers to guide us and take care of us. Jesus identified Himself as the Good Shepherd. As such, He differs from false shepherds who neither care for nor protect the sheep (John 10:1, 10, 12–13). By contrast, Jesus the Good Shepherd leads His sheep (John 10:3). He goes before them to show the way and to protect them (John 10:4). Later in John 10 Jesus spoke further of His protection of believers. He said in verse 28: "I give them eternal life, and they will never perish, and no one will snatch them out of my hand" (John 10:28).