What does Genesis 27:45 mean?

Esau has a plan to kill Jacob (Genesis 27:41). His rage is sinful, but not unexpected. Jacob conspired with their mother, Rebekah, to fool their blind father, Isaac, into giving a blessing to Jacob instead of Esau (Genesis 27:1–6; 30–35). Rebekah has learned of Esau's vengeful intentions. She is compelling Jacob, actually commanding him, to run for his life to her brother's household in Mesopotamia (Genesis 24:1–4; 24:23–28). She tells Jacob she wants him to stay there until Esau forgets that Jacob has stolen Isaac's blessing from him. She wants Jacob to stay far away until Esau's fury passes (Genesis 27:43–44).

She promises to send for Jacob when that day comes, though she gives no clue about when it might be. She does describe her greatest fear: losing both of her sons. If Esau kills him, Jacob would be dead and then Esau himself would likely be killed or sent away. She desperately wants to prevent that. As it turns out, Rebekah's plot will cost her a relationship with the son she greatly favors (Genesis 25:28). So far as we can tell from Scripture, Jacob will not return until after Rebekah has died (Genesis 35:27; 49:31).