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Verse
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Isaiah 2:22
ESV Stop regarding man in whose nostrils is breath, for of what account is he?
NIV Stop trusting in mere humans, who have but a breath in their nostrils. Why hold them in esteem?
NASB Take no account of man, whose breath of life is in his nostrils; For why should he be esteemed?
CSB Put no more trust in a mere human, who has only the breath in his nostrils. What is he really worth?
NLT Don’t put your trust in mere humans. They are as frail as breath. What good are they?
KJV Cease ye from man, whose breath is in his nostrils: for wherein is he to be accounted of?

What does Isaiah 2:22 mean?

Isaiah concludes chapter two with a warning for those wise enough to hear it. The lesson is to stop trusting in mere human beings to save you. They may be wealthy and seemingly secure for the moment, but it's foolish to follow their path of destruction through worshipping idols (Isaiah 2:8),visiting soothsayers, and making deals with foreign governments (Isaiah 2:6). At the end of the day, human beings are always just one breath away from death (James 4:14). The day of the Lord will come, and those who have not trusted in Him will be destroyed (Ezekiel 30:3; Obadiah 1:15; Acts 2:20; 2 Peter 3:10). Seemingly important peoples' power will be revealed as a fleeting moment of arrogance and not a plan for success.

The crucial, overall message of this passage is the need to trust God, not human beings. His power is genuine and eternal (Romans 1:18–21; 1 Timothy 6:15–16).
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