What does Genesis 12:10 mean?
After spending some time in the land God has promised to his offspring, Abram and his large company are forced to leave Canaan. The land of the Negeb, where Abram's family has most recently been (Genesis 12:9), is dry and hilly. It was prone to famine in seasons of drought, especially before modern methods of farming came along.A severe famine, then would most likely have forced most inhabitants of the region to travel to find resources. There simply was no food or water to support them in the Negeb. Egypt, on the other hand, had the advantage of the flat lowlands along the Nile river. People of the surrounding regions often immigrated to Egypt hoping to survive a famine.
Abram will not be the last of the patriarchs, the fathers of Israel, to move to Egypt in a time of drought. The sons of Jacob, Abram's grandson, will travel there to seek food and encounter their estranged brother, Joseph (Genesis 37—47).
Genesis 12:10–20 tells a story of Abram's fearfulness and God's faithful intervention to keep His promises. A famine forces Abram's large company to enter the land of Egypt in search of food. Pharaoh's sons quickly notice Sarai's great beauty, and Pharaoh takes her for one of his wives. This occurs because Abram, fearful for his life, has claimed that Sarai is his sister. In spite of Abram's lie and failure to trust Him, God afflicts Pharaoh's household for this dishonor, bringing the truth to light. Pharaoh, angry and fearful, sends Abram, Sarai, and the company back to the land of Canaan.
Genesis 12 contains one of the key moments in the history of the world. God chooses Abram as the first step in building His people Israel. Abram obeys God's call, and heads into the land of Canaan, territory which God promises to Abram's offspring. Quickly, though, Abram fails a test of faith in the land of Egypt while seeking food in a famine. God does not fail, however, to step in to save Abram's family and protect His agenda for Abram's life.